Paracil 500mg Paracetamol Tablets 1,000s

Paracil 500mg Paracetamol Tablets 1,000s is a registered non-prescription analgesic and antipyretic containing paracetamol 500mg in each tablet.

Paracil is used for the temporary relief of mild to moderate pain and for reducing fever. The P-Hub bulk presentation contains 1,000 tablets arranged as 100 blister strips of 10 tablets.

Paracil contains paracetamol. It must not be taken together with another medicine containing paracetamol because accidental duplication can cause a dangerous overdose and serious liver damage.

Paracil 500mg Product Information

What Is Paracil 500mg Used For?

Paracil is used for temporary relief of mild to moderate pain and for reducing fever.

It may be used for symptoms such as:

• Headache
• Tension headache
• Migraine-related pain
• Toothache
• Muscular aches
• Backache
• Joint or arthritic pain
• Period pain
• Sore throat discomfort
• Aches and discomfort associated with colds or influenza
• Fever

Paracetamol temporarily reduces pain and fever. It does not treat the underlying cause of an infection, injury or inflammatory condition.

How Paracil Works

Paracetamol acts mainly within the central nervous system. Its analgesic effect helps reduce the perception of pain, while its antipyretic effect acts on temperature-regulating centres in the brain to help lower fever.

The precise mechanism is not completely understood, but it is believed to involve inhibition of prostaglandin production primarily within the central nervous system.

Paracetamol does not have the same degree of peripheral anti-inflammatory activity as non-steroidal anti-inflammatory medicines such as ibuprofen or naproxen.

How Long Does Paracil Take to Work?

Standard immediate-release paracetamol generally begins to relieve pain and reduce fever within approximately 30 minutes.

Its effect commonly lasts for around four hours, although the response varies according to the patient, condition, dose and other clinical factors.

How to Take Paracil 500mg

Follow the dosage printed on the Malaysian package, dispensing label or instructions provided by a doctor or pharmacist.

Adult and Adolescent Reference Dosage

For adults and adolescents aged 12 years and above, general reference guidance for standard paracetamol 500mg tablets is:

• Take one or two tablets when required.
• Leave at least four hours between doses.
• The dose may be repeated every four to six hours when necessary.
• Do not take more than two tablets in one dose.
• Do not take more than eight tablets, equivalent to 4,000mg, within 24 hours.
• Use the lowest effective dose for the shortest necessary period.

The maximum of eight tablets daily is not appropriate for every patient. A lower dose or longer interval may be necessary for patients with liver disease, kidney impairment, low body weight, malnutrition, frailty, chronic heavy alcohol use or another risk factor for paracetamol toxicity.

Children

Paracetamol dosing in children should be based on age and body weight. A 500mg tablet may be unsuitable for younger children or may not provide the required dose accurately.

• Do not apply the adult dose to a child.
• Use an age-appropriate paediatric formulation whenever necessary.
• Check the child’s weight and the strength of every paracetamol product.
• Do not give more than the number of doses permitted within 24 hours.
• Seek advice from a doctor or pharmacist when the appropriate dose is uncertain.

The Malaysian Paracil package insert and professional instructions should take precedence over general dosing information.

Can Paracil Be Taken With Food?

Paracil may generally be taken with or without food.

Swallow the tablet with water. Food may delay absorption slightly, but it does not normally prevent paracetamol from working.

What to Do If a Dose Is Missed

Paracil is commonly used only when pain or fever is present, so a missed dose may not need to be replaced.

If it is being taken according to a regular schedule:

• Take the missed dose when remembered unless the next dose is due soon.
• Ensure that at least four hours separates the doses.
• Do not take a double dose.
• Do not exceed the permitted total amount within 24 hours.

Do Not Combine With Other Paracetamol Products

Many medicines contain paracetamol even when the product name does not clearly include the word “paracetamol.”

Before taking Paracil, check all other products being used, including:

• Cold and influenza medicines
• Headache and migraine products
• Night-time pain or sleep medicines
• Combination medicines containing paracetamol and ibuprofen
• Prescription pain medicines containing paracetamol and codeine
• Prescription pain medicines containing paracetamol and tramadol
• Paracetamol liquids, powders, suppositories or modified-release tablets

When in doubt, ask a pharmacist to calculate the total amount of paracetamol being taken from every source.

Paracetamol Overdose Warning

Taking too much paracetamol can cause severe liver damage, liver failure, the need for liver transplantation or death.

Overdose may occur because of:

• Taking more than the recommended number of tablets
• Taking doses too close together
• Using several paracetamol-containing products at the same time
• Using adult-strength tablets in a child
• Misunderstanding the difference between standard and modified-release paracetamol
• Continuing high doses while malnourished, unwell or consuming substantial alcohol

Seek urgent medical attention immediately if an overdose has been taken or is suspected, even when the person feels well and has no symptoms.

Early symptoms may be mild or absent. Serious liver injury may not become apparent until 24 to 48 hours after the overdose. Treatment is most effective when started promptly.

Do not wait for abdominal pain, vomiting, jaundice or another symptom to develop before seeking emergency assessment.

Who Should Not Take Paracil?

Do not take Paracil if the patient has:

• A known allergy to paracetamol
• An allergy to another ingredient in the tablet
• Already taken the maximum permitted amount of paracetamol within the preceding 24 hours
• Already taken another medicine containing paracetamol and the total dose cannot be confirmed

Patients with severe liver disease or another significant medical condition should obtain professional advice before using paracetamol.

Consult a Healthcare Professional Before Use

Ask a doctor or pharmacist before taking Paracil if the patient:

• Has liver disease or abnormal liver-function results
• Has kidney impairment
• Regularly consumes substantial quantities of alcohol
• Has a low body weight
• Is undernourished, anorexic or severely malnourished
• Has sepsis or another severe infection
• Is dehydrated
• Is elderly or frail
• Is taking warfarin or another anticoagulant
• Is taking medicines for epilepsy
• Is taking flucloxacillin or another potentially interacting medicine
• Is pregnant, planning a pregnancy or breastfeeding
• Requires paracetamol regularly for more than a few days

Liver-Disease and Alcohol Precautions

Paracetamol is mainly metabolised in the liver. Underlying liver disease can increase the risk of paracetamol-related liver injury.

Chronic heavy alcohol use may also increase risk, particularly when combined with:

• Fasting
• Low body weight
• Malnutrition
• Repeated high paracetamol doses
• Another medicine that affects the liver

Patients who regularly consume substantial amounts of alcohol should obtain professional advice regarding whether paracetamol is appropriate and what maximum dose should be used.

Kidney-Impairment Precautions

Patients with moderate or severe kidney impairment may require a longer interval between doses or another dosage adjustment.

Kidney impairment can affect the elimination of paracetamol metabolites. The appropriate regimen should be determined by a doctor or pharmacist.

High Anion Gap Metabolic Acidosis

A rare condition known as high anion gap metabolic acidosis due to pyroglutamic acid accumulation has been reported in patients taking paracetamol, especially during prolonged use in patients with significant risk factors.

Risk factors may include:

• Severe kidney impairment
• Sepsis or another serious illness
• Malnutrition
• Chronic heavy alcohol use
• Reduced glutathione levels
• Concurrent flucloxacillin treatment

Seek urgent medical assessment for deep or rapid breathing, severe nausea, vomiting, unusual drowsiness, confusion or loss of appetite in a high-risk patient taking paracetamol.

Possible Side Effects

Side effects are uncommon when paracetamol is taken at the recommended dose for a short period.

Possible reactions include:

• Skin rash
• Itching or hives
• Nausea or abdominal discomfort
• Unexplained bruising or bleeding
• Changes in blood-cell counts
• Liver-function abnormalities

Stop taking the medicine and obtain professional advice if an unexpected reaction occurs.

Serious Reactions Requiring Urgent Medical Attention

Stop taking Paracil and seek urgent medical attention for:

• Swelling of the face, lips, tongue or throat
• Difficulty breathing, wheezing or swallowing
• A severe, blistering, peeling or widespread skin reaction
• Mouth ulcers with a severe rash
• Unexplained bruising or bleeding
• Yellowing of the skin or eyes
• Dark urine or pale stools
• Severe upper abdominal pain
• Deep or rapid breathing with nausea, vomiting or drowsiness
• Any suspected overdose

Medicine Interactions

Tell the doctor or pharmacist about all prescription medicines, non-prescription products, traditional medicines and supplements being used.

Medicines requiring particular consideration include:

• Warfarin and other coumarin anticoagulants: prolonged regular daily paracetamol use may increase the anticoagulant effect and bleeding risk. Occasional doses are less likely to have a significant effect.
• Metoclopramide: may increase the rate at which paracetamol is absorbed.
• Cholestyramine: may reduce paracetamol absorption when taken within approximately one hour.
• Probenecid: may alter paracetamol elimination and may require dosage review.
• Chloramphenicol: paracetamol may affect chloramphenicol concentrations.
• Antiepileptic medicines: enzyme-inducing medicines may increase the risk of liver toxicity in susceptible patients.
• Flucloxacillin: combined use has been associated with high anion gap metabolic acidosis in patients with relevant risk factors.
• Other medicines that affect the liver: combined use may increase the risk of liver injury.
• Other paracetamol-containing products: combined use can cause accidental overdose and must be avoided.

Pregnancy and Breastfeeding

Paracetamol may be used during pregnancy when clinically necessary and taken at the recommended dose for the shortest appropriate period.

Pregnant patients should obtain professional advice when:

• Pain or fever is severe or persistent
• Repeated doses are required
• Another medicine is being used
• There is liver or kidney disease
• The correct dose is uncertain

Paracetamol passes into breast milk in small amounts and is generally compatible with breastfeeding when taken at the recommended dosage. The lowest effective dose should be used for the shortest necessary period.

Use in Older Adults

A dose adjustment is not automatically required solely because of age. However, older adults may be more likely to have:

• Low body weight
• Frailty or malnutrition
• Liver or kidney impairment
• Multiple concurrent medicines
• Increased risk of accidental duplicate dosing

The maximum appropriate dose should therefore be assessed individually.

When to Seek Medical Advice for Pain or Fever

Consult a doctor or pharmacist if:

• Pain is severe, unexplained or worsening
• Pain continues for more than a few days
• Fever persists or repeatedly returns
• Symptoms occur in a very young child
• There is a stiff neck, confusion, seizure or severe headache
• There is chest pain or difficulty breathing
• There is severe abdominal pain
• There is persistent vomiting or dehydration
• A rash develops with fever
• There is concern about the amount of paracetamol already taken

Storage Instructions

• Store according to the conditions printed on the Malaysian carton or blister.
• Keep the tablets in their original blister strips until required.
• Protect from heat, moisture and direct sunlight.
• Do not store in a bathroom, near a sink or inside a hot vehicle.
• Keep out of sight and reach of children.
• Do not use tablets that appear wet, cracked, discoloured or damaged.
• Do not use after the expiry date printed on the carton or blister.
• Expiry varies by supplied batch.

Bulk-Pack Handling Information

The 1,000-tablet presentation is intended for professional pharmacy procurement and supply.

• Maintain batch-number and expiry-date traceability.
• Keep the outer carton and original blister strips together.
• Do not supply damaged or unidentified strips.
• Provide the applicable medicine information and dosage instructions when dispensing.
• Dispense and label the product according to applicable Malaysian pharmacy requirements.

Frequently Asked Questions

What is the active ingredient in Paracil 500mg?

Each tablet contains paracetamol 500mg.

What is Paracil used for?

Paracil is used for temporary relief of mild to moderate pain and for reducing fever.

Is Paracil the same type of medicine as Panadol?

Paracil and standard Panadol products may both contain paracetamol. However, patients should compare the strength, formulation and dosage instructions rather than assuming that every product is interchangeable.

Is paracetamol also called acetaminophen?

Yes. Paracetamol is known as acetaminophen in some countries.

How many tablets are supplied in this pack?

The P-Hub bulk presentation contains 1,000 tablets arranged as 100 blister strips of 10 tablets.

How quickly does Paracil work?

Standard paracetamol commonly begins to relieve pain and fever within approximately 30 minutes.

How often can adults take Paracil?

General reference guidance is one or two 500mg tablets every four to six hours when required, with at least four hours between doses.

What is the maximum adult dose?

The general maximum for a healthy adult is eight 500mg tablets, equivalent to 4,000mg, within 24 hours. A lower maximum may be required for patients with liver or kidney impairment, low body weight, malnutrition, frailty or substantial alcohol use.

Can two Paracil tablets be taken together?

Two tablets provide a 1,000mg dose. This may be permitted for suitable adults and adolescents aged 12 years and above, but the product label, individual risk factors and total daily dose must be considered.

Can Paracil be taken with food?

Yes. It may generally be taken with or without food and swallowed with water.

Can Paracil be taken with a cold or influenza medicine?

Only when the other product has been confirmed not to contain paracetamol. Many cold and influenza products already contain paracetamol.

Can Paracil be taken with Panadol?

No, not as an additional dose. Standard Panadol products commonly contain paracetamol, so taking both may duplicate the active ingredient and cause an overdose.

Can Paracil be taken with ibuprofen?

Paracetamol and ibuprofen are different medicines and may sometimes be used together. However, suitability depends on the patient’s age, medical conditions, other medicines and exact products being used. Obtain professional advice where necessary.

Can children take Paracil 500mg?

A 500mg tablet may be unsuitable for younger children. Paediatric paracetamol dosing should be based on age and weight using an appropriate formulation and professional instructions.

Can Paracil be used during pregnancy?

Paracetamol may be used during pregnancy when clinically necessary at the recommended dose for the shortest appropriate period. Pregnant patients should seek advice when repeated treatment is required.

Can Paracil be used while breastfeeding?

Paracetamol is generally compatible with breastfeeding when used at the recommended dose.

Can a patient with liver disease take Paracil?

Patients with liver disease must obtain professional advice before using paracetamol. A lower dose or avoidance may be necessary depending on the condition.

Can a patient taking warfarin use Paracil?

Occasional paracetamol doses are less likely to have a significant effect, but prolonged regular use may increase warfarin’s anticoagulant effect and bleeding risk. Professional monitoring may be required.

What should be done after taking too much Paracil?

Seek emergency medical attention immediately, even when there are no symptoms. Do not wait for signs of liver injury to appear.

Is Paracil a prescription medicine in Malaysia?

No. Paracil Tablet 500mg is registered under the Non-Prescription-Full classification. It must nevertheless be used according to the approved label and dosage instructions.

What is the Malaysian registration number?

The Malaysian registration number is MAL19940551XZ.

Who manufactures Paracil 500mg?

Paracil Tablet 500mg is registered to and manufactured in Malaysia by SM Pharmaceuticals Sdn. Bhd.

Can pharmacies request Paracil through P-Hub?

Paracil 500mg Paracetamol Tablets 1,000s is listed in the P-Hub B2B catalogue for approved pharmacy members. Quotation, ordering eligibility and supply are subject to P-Hub membership requirements and current stock availability.

Non-Prescription Medicine Notice

Paracil 500mg is a registered non-prescription medicine. Read the product label and package insert before use. Do not exceed the recommended dose or combine it with another paracetamol-containing medicine.

Paracetamol overdose can cause delayed, severe and potentially fatal liver damage. Obtain urgent medical attention immediately after a suspected overdose, even when the person feels well.

The information on this page is provided for pharmacy catalogue and professional product-reference purposes. It does not replace the approved Malaysian package insert, an individual medical assessment or advice from a qualified healthcare professional.

Product appearance, packaging, batch number, availability and expiry date may vary. Verify all information on the physical Malaysian carton, blister strips and approved insert before dispensing or use.

Product Information Sources

• NPRA Malaysia – Paracil Tablet 500mg Registration Renewal
  
• Medsafe – Paracetamol 500mg Professional Data Sheet
  
• Medsafe – Paracetamol 500mg Consumer Medicine Information
  
• Healthdirect Australia – Paracetamol Uses and Safety Information
  

Product information last reviewed: 12 July 2026.