Lipanthyl Penta 145mg Fenofibrate Tablets 30s

Lipanthyl Penta 145mg Fenofibrate Tablets 30s is a prescription lipid-regulating medicine containing fenofibrate 145mg in each film-coated tablet. Fenofibrate belongs to a group of medicines known as fibrates.

Lipanthyl Penta 145 is used alongside an appropriate diet, physical activity, weight management and other non-drug measures for selected patients with high triglyceride or mixed blood-lipid disorders.

It may also be prescribed to reduce the progression of diabetic retinopathy in patients with type 2 diabetes and existing diabetic retinopathy. Lipanthyl does not replace appropriate control of blood glucose, blood pressure and blood lipids.

Lipanthyl Penta 145mg Product Information

What Is Lipanthyl Penta 145mg Used For?

Lipanthyl Penta 145 may be prescribed as an addition to diet and other non-pharmacological measures for selected blood-lipid disorders.

Severe Hypertriglyceridaemia

Fenofibrate may be used for severe hypertriglyceridaemia, with or without a low level of high-density lipoprotein cholesterol. Triglycerides are a type of fat carried in the blood.

Very high triglyceride levels may increase the risk of complications, including inflammation of the pancreas. Treatment should be accompanied by dietary and lifestyle measures recommended by the healthcare professional.

Mixed Hyperlipidaemia

Lipanthyl Penta may be prescribed for mixed hyperlipidaemia when a statin is contraindicated, unsuitable or not tolerated.

It may also be prescribed together with a statin in selected patients at high cardiovascular risk when triglyceride and HDL cholesterol levels remain inadequately controlled. Combination therapy requires professional assessment because the risk of muscle-related adverse effects may increase.

Secondary Hyperlipoproteinaemia

Fenofibrate may be considered when abnormal blood-lipid levels persist despite effective treatment of an underlying condition, such as dyslipidaemia associated with diabetes mellitus.

Diabetic Retinopathy

Lipanthyl Penta 145 is approved in Malaysia to reduce the progression of diabetic retinopathy in patients with type 2 diabetes and existing diabetic retinopathy.

Diabetic retinopathy is an eye complication caused by diabetes-related damage to blood vessels in the retina. Fenofibrate treatment does not replace regular eye examinations or appropriate management of blood glucose, blood pressure and blood-lipid levels.

How Lipanthyl Penta Works

Fenofibrate activates peroxisome proliferator-activated receptor alpha, commonly abbreviated as PPAR-alpha. This affects the way the body processes triglycerides and other lipoproteins.

Its lipid-regulating effects may include:

• Reducing triglyceride-rich lipoproteins
• Increasing the breakdown and removal of certain blood fats
• Reducing selected forms of cholesterol
• Increasing HDL cholesterol in some patients

The individual response should be assessed using blood tests. Fenofibrate should not be considered a substitute for dietary changes, exercise, weight management or treatment of an underlying medical condition.

How to Take Lipanthyl Penta 145mg

• Take Lipanthyl Penta exactly as prescribed by the treating doctor.
• The recommended adult reference dose is one 145mg tablet once daily.
• The tablet may be taken with or without food.
• Swallow the tablet whole with a glass of water.
• Do not crush, chew or dissolve the tablet.
• Take the medicine at approximately the same time each day.
• Continue the prescribed diet and lifestyle programme.
• Do not increase, reduce or stop treatment without professional advice.

Patients using fenofibrate for both a lipid disorder and diabetic retinopathy should not take an additional tablet for the second indication. The approved reference dosage remains one 145mg tablet daily unless the treating doctor provides different instructions.

What to Do If a Dose Is Missed

Take the missed dose when remembered unless it is nearly time for the next scheduled dose. If the next dose is approaching, skip the missed dose and continue with the normal schedule.

Do not take two tablets together to replace a missed dose. Consult a doctor or pharmacist if several doses have been missed or there is uncertainty about restarting treatment.

Monitoring During Treatment

A healthcare professional may monitor:

• Triglyceride and cholesterol levels
• Liver-function test results
• Kidney function and serum creatinine
• Muscle symptoms and creatine kinase when clinically necessary
• Blood glucose and diabetes control
• Diabetic-retinopathy progression where applicable

The response to lipid treatment should be assessed periodically. If an adequate response has not been achieved after several months, the doctor may consider additional or alternative treatment.

Important Safety Information

• Lipanthyl Penta is a prescription medicine and should not be shared with another person.
• Continue the diet and lifestyle measures recommended before treatment.
• Tell the doctor about kidney, liver, gallbladder, thyroid or pancreatic conditions.
• Report unexplained muscle pain, tenderness, cramps or weakness promptly.
• Tell the prescriber about statins, anticoagulants, ciclosporin and all other medicines being used.
• Seek medical attention for severe abdominal pain, jaundice or a serious skin reaction.
• Attend all scheduled blood tests, medical reviews and eye examinations.

Who Should Not Take Lipanthyl Penta?

Lipanthyl Penta may be contraindicated in patients with:

• An allergy to fenofibrate or another ingredient in the tablet
• An allergy to peanuts, arachis oil, soybean lecithin or related products
• Severe chronic kidney disease
• Liver insufficiency, biliary cirrhosis or persistent unexplained liver-function abnormalities
• Known gallbladder disease
• Chronic or acute pancreatitis, except pancreatitis caused by severe hypertriglyceridaemia
• A previous photoallergic or phototoxic reaction during treatment with a fibrate or ketoprofen

The doctor should review the patient’s medical history, kidney function, liver function and complete medication list before treatment begins.

Kidney Function Considerations

Fenofibrate is not suitable at the 145mg strength for patients with severe kidney impairment. Dose reduction or an alternative lower-strength formulation may be required for moderate kidney impairment.

Kidney function should be assessed before treatment and periodically afterward, particularly in older patients and those with diabetes or existing kidney disease.

Contact the treating doctor if there is a significant reduction in urine output, severe dehydration or an unexpected deterioration in general health.

Liver and Gallbladder Precautions

Fenofibrate may affect liver enzymes. Liver-function testing may be required before and during treatment.

Obtain medical advice if symptoms occur such as:

• Yellowing of the skin or eyes
• Dark urine
• Persistent nausea or loss of appetite
• Unusual tiredness
• Pain in the upper abdomen

Fenofibrate may increase cholesterol excretion into bile and may contribute to gallstone formation in susceptible patients. Severe upper abdominal pain, particularly with nausea or vomiting, requires medical assessment.

Muscle Pain and Rhabdomyolysis Warning

Fibrates can occasionally cause muscle toxicity, including myopathy and the rare but serious condition known as rhabdomyolysis.

The risk may be greater in patients who:

• Take a statin or another fibrate
• Have kidney impairment
• Have untreated hypothyroidism
• Are older than 70 years
• Have a personal or family history of inherited muscle disorders
• Consume excessive amounts of alcohol

Stop taking the medicine and obtain prompt medical advice if unexplained muscle pain, tenderness, weakness or cramps occur, particularly when accompanied by fever, dark urine or feeling unwell.

Pancreatitis Warning

Pancreatitis has been reported during fenofibrate treatment. Severe or persistent upper abdominal pain that may spread to the back, particularly with nausea or vomiting, requires urgent medical assessment.

Pancreatitis may be associated with treatment failure in severe hypertriglyceridaemia, gallstones or another medical cause.

Possible Side Effects

Not everyone experiences side effects. Possible effects associated with fenofibrate include:

• Abdominal pain or digestive discomfort
• Nausea or vomiting
• Diarrhoea or flatulence
• Headache
• Increased liver enzymes
• Increased serum creatinine
• Skin rash, itching or sensitivity to sunlight
• Muscle pain, tenderness or weakness
• Gallstones

Persistent, worsening or troublesome effects should be discussed with a doctor or pharmacist.

Serious Symptoms Requiring Medical Attention

Seek prompt or urgent medical attention if any of the following occurs:

• Severe or unexplained muscle pain or weakness
• Dark-coloured urine with muscle symptoms
• Severe or persistent abdominal pain
• Yellowing of the skin or eyes
• Swelling of the face, lips, tongue or throat
• Difficulty breathing or swallowing
• A severe, blistering or widespread skin reaction
• Severe sensitivity or blistering after sunlight exposure
• Another serious or unexpected reaction

Medicine Interactions

Tell the doctor and pharmacist about all prescription medicines, non-prescription products, traditional medicines and supplements being used.

Medicines requiring particular consideration include:

• Statins: combined use may increase the risk of myopathy and rhabdomyolysis.
• Other fibrates: duplication may increase muscle and other adverse effects.
• Warfarin and other coumarin anticoagulants: fenofibrate may increase the anticoagulant effect and bleeding risk. Dose adjustment and closer clotting-test monitoring may be required.
• Ciclosporin: combined use may increase the risk of kidney impairment and requires close monitoring.
• Glitazone diabetes medicines: medicines such as pioglitazone may rarely be associated with a significant reduction in HDL cholesterol when combined with a fibrate.
• Medicines affecting kidney or liver function: additional monitoring may be required.

Do not start, stop or change another medicine without consulting the treating doctor or pharmacist.

Pregnancy and Breastfeeding

Patients who are pregnant, planning a pregnancy or think they may be pregnant should inform their doctor before taking Lipanthyl Penta.

Fenofibrate should only be considered during pregnancy when the treating doctor determines that the expected benefit justifies the potential risk.

Lipanthyl Penta is not recommended during breastfeeding because it is not known whether fenofibrate or its metabolites pass into human milk.

Use in Children and Adolescents

The safety and effectiveness of Lipanthyl Penta 145 have not been established in patients below 18 years old. It is not recommended for children or adolescents unless specifically prescribed under appropriate specialist supervision.

Storage Instructions

• Store according to the conditions printed on the Malaysian carton and package insert.
• Keep the tablets in their original blister packaging until required.
• Protect from excessive heat and moisture.
• Keep out of reach of children.
• Do not use tablets that appear wet, damaged, discoloured or deteriorated.
• Do not use after the expiry date printed on the supplied packaging.
• Product appearance, packaging, batch number and expiry date may vary between supplied batches.

Frequently Asked Questions

What is the active ingredient in Lipanthyl Penta 145mg?

Each Lipanthyl Penta film-coated tablet contains fenofibrate 145mg.

What type of medicine is Lipanthyl Penta?

Lipanthyl Penta is a fibrate lipid-regulating medicine used to manage selected triglyceride and cholesterol disorders.

What is Lipanthyl Penta 145mg used for?

It is used alongside diet and lifestyle measures for selected severe triglyceride and mixed lipid disorders. In Malaysia, it is also approved to reduce the progression of diabetic retinopathy in patients with type 2 diabetes and existing diabetic retinopathy.

Is Lipanthyl Penta a statin?

No. Lipanthyl Penta contains fenofibrate, which belongs to the fibrate class. Statins and fibrates lower blood lipids through different mechanisms.

Can Lipanthyl Penta be taken together with a statin?

A doctor may prescribe fenofibrate together with a statin for selected high-risk patients whose triglyceride and HDL cholesterol levels remain inadequately controlled. The combination requires professional monitoring because muscle-related adverse effects may increase.

Can Lipanthyl Penta be taken with food?

Yes. Lipanthyl Penta 145 may be taken with or without food. The tablet should be swallowed whole with water.

How often is Lipanthyl Penta 145mg taken?

The approved adult reference dosage is one 145mg tablet once daily. Patients must follow the dosage stated on their individual prescription.

Does Lipanthyl Penta treat diabetic retinopathy?

Lipanthyl Penta is approved to reduce the progression of diabetic retinopathy in patients with type 2 diabetes and existing diabetic retinopathy. It does not replace eye examinations or appropriate blood-glucose, blood-pressure and lipid management.

Can Lipanthyl Penta cause muscle pain?

Yes. Unexplained muscle pain, tenderness, cramps or weakness should be reported promptly, especially when Lipanthyl Penta is taken with a statin.

Can patients with kidney disease take Lipanthyl Penta 145mg?

The 145mg strength is contraindicated in severe chronic kidney disease and may be unsuitable in moderate kidney impairment. Kidney function should be assessed before treatment.

Can patients with peanut or soy allergy take Lipanthyl Penta?

No. The approved product information states that Lipanthyl Penta should not be taken by patients allergic to peanuts, arachis oil, soybean lecithin or related products.

Is Lipanthyl Penta a prescription medicine in Malaysia?

Yes. Lipanthyl Penta 145mg is a prescription medicine and should only be supplied and used according to a valid prescription and professional instructions.

What is the Malaysian registration number?

The Malaysian registration number for Lipanthyl Penta 145 is MAL10053648AZ.

Who manufactures Lipanthyl Penta 145mg?

The Malaysian product is registered to Abbott Laboratories (M) Sdn. Bhd. and manufactured by Fournier Laboratories Ireland Limited, Ireland.

How many tablets are supplied in one pack?

The P-Hub listing contains 30 tablets, supplied as three blister strips of ten tablets.

Can pharmacies request Lipanthyl Penta through P-Hub?

Lipanthyl Penta 145mg Fenofibrate Tablets 30s is listed in the P-Hub B2B catalogue for approved pharmacy members. Quotation, ordering eligibility and supply are subject to P-Hub membership requirements, prescription medicine controls and current stock availability.

Prescription Medicine Notice

Lipanthyl Penta 145mg is a prescription medicine. It should only be supplied, dispensed and used according to applicable Malaysian requirements and the directions of a registered doctor or pharmacist.

The information on this page is provided for pharmacy catalogue and professional product-reference purposes. It does not replace an individual medical assessment, lipid-management plan, prescription, approved Malaysian package insert or advice from a qualified healthcare professional.

Product appearance, packaging, batch number, availability and expiry date may vary. Verify all information on the physical product packaging and approved insert before dispensing or use.

Product Information Sources

• National Pharmaceutical Regulatory Agency Malaysia – Lipanthyl Penta Registration Renewal
  
• National Pharmaceutical Regulatory Agency Malaysia – Diabetic Retinopathy Indication
  
• Singapore National Drug Formulary – Lipanthyl Penta 145 Product Information
  
• Abbott – Lipanthyl Product Overview
  

Product information last reviewed: 11 July 2026.