Forxiga 10mg Dapagliflozin Tablets 28s

Forxiga is prescribed for selected adults with type 2 diabetes mellitus, symptomatic chronic heart failure or chronic kidney disease. The appropriate indication, treatment duration and monitoring requirements depend on the patient’s diagnosis, kidney function, concurrent medicines and overall clinical condition.

Forxiga is not intended for self-selection, general weight-loss use, treatment of type 1 diabetes or treatment of diabetic ketoacidosis.

Forxiga 10mg Dapagliflozin Product Information

What Is Forxiga 10mg Used For?

Forxiga 10mg may be prescribed for selected adult patients with type 2 diabetes mellitus, symptomatic chronic heart failure or chronic kidney disease.

Type 2 Diabetes Mellitus

Forxiga may be used with an appropriate diet and physical-activity programme to improve blood-glucose control in adults with type 2 diabetes mellitus.

It may be prescribed as monotherapy when metformin is considered inappropriate because of intolerance or as an additional treatment with other glucose-lowering medicines when existing treatment does not provide adequate control.

When Forxiga is combined with insulin or a sulfonylurea, the doctor may review the dosage of those medicines because the risk of hypoglycaemia may increase.

Symptomatic Chronic Heart Failure

Forxiga is approved in Malaysia for the treatment of symptomatic chronic heart failure in adults.

Heart failure occurs when the heart cannot pump blood around the body as effectively as required. Symptoms may include breathlessness, fatigue, reduced exercise tolerance and swelling of the ankles or legs.

Forxiga is used as part of an overall heart-failure treatment plan and does not replace other prescribed heart medicines unless the treating doctor provides specific instructions.

Chronic Kidney Disease

Forxiga is also approved in Malaysia for the treatment of chronic kidney disease in adults.

Chronic kidney disease is a long-term condition in which kidney function gradually declines. The suitability of dapagliflozin treatment depends on the patient’s kidney function, underlying cause of kidney disease and existing treatment plan.

How Forxiga Works

SGLT2 proteins in the kidneys normally help return filtered glucose from the urine to the bloodstream.

Dapagliflozin blocks SGLT2 activity. This allows more glucose, sodium and water to be removed from the body through the urine.

In patients with type 2 diabetes, this mechanism helps lower blood-glucose levels. Dapagliflozin also produces cardiovascular and kidney effects that support its approved uses in selected adults with heart failure and chronic kidney disease.

How to Take Forxiga 10mg

• Take Forxiga exactly as prescribed by the treating doctor.
• The approved reference dose is generally one 10mg tablet once daily.
• Swallow the tablet whole with water.
• Forxiga may be taken with or without food.
• The tablet may be taken at any time of day, but it should preferably be taken at approximately the same time each day.
• Do not increase, reduce or stop treatment without professional advice.
• Continue any diet, physical-activity, fluid-management or monitoring plan recommended by the healthcare professional.

The prescribed treatment may differ for patients with severe liver impairment or other significant clinical considerations. Instructions on the dispensing label and approved Malaysian package insert take precedence over general product information.

What to Do If a Dose Is Missed

• If there are 12 hours or more before the next scheduled dose, take the missed tablet when remembered.
• If there are fewer than 12 hours before the next dose, skip the missed tablet.
• Take the next dose at the usual scheduled time.
• Do not take two doses to compensate for a missed dose.

Consult a doctor or pharmacist if several doses have been missed or there is uncertainty about restarting treatment.

Monitoring During Treatment

A healthcare professional may monitor:

• Kidney function
• Blood-glucose control in patients with diabetes
• Blood pressure
• Hydration and fluid status
• Electrolyte levels when clinically appropriate
• Symptoms of urinary or genital infection
• Heart-failure symptoms where applicable
• Signs of diabetic ketoacidosis in patients at increased risk

Kidney function remains relevant even when Forxiga is prescribed for heart failure or chronic kidney disease. Patients should attend all laboratory tests and follow-up appointments arranged by the treating healthcare professional.

Important Safety Information

• Forxiga is a prescription medicine and should not be shared with another person.
• It should not be used to treat type 1 diabetes.
• It must not be used to treat diabetic ketoacidosis.
• It is not approved as a general weight-loss medicine.
• Tell the doctor about kidney disease, liver disease, low blood pressure or recurrent urinary infections.
• Tell the doctor about severe vomiting, diarrhoea, fever, reduced food intake or dehydration.
• Maintain appropriate fluid intake unless a healthcare professional has advised fluid restriction.
• Inform the treating team before major surgery, prolonged fasting or hospitalisation for a serious illness.
• Tell the prescriber about insulin, sulfonylureas, diuretics, lithium and all other medicines being used.

Diabetic Ketoacidosis Warning

SGLT2 inhibitors, including dapagliflozin, have been associated with diabetic ketoacidosis, commonly abbreviated as DKA. This is a serious and potentially life-threatening condition caused by excessive ketone accumulation.

DKA associated with SGLT2 inhibitors may occur even when the blood-glucose level is only moderately elevated or appears close to the expected range.

Stop taking Forxiga and seek urgent medical attention if symptoms occur such as:

• Nausea or vomiting
• Abdominal pain
• Loss of appetite
• Excessive thirst
• Rapid or unusually deep breathing
• Difficulty breathing
• Confusion
• Unusual tiredness or sleepiness
• Sweet or unusual-smelling breath
• Rapid or unexplained weight loss

The risk of DKA may increase during prolonged fasting, severe dehydration, major surgery, acute serious illness, excessive alcohol consumption, sudden insulin-dose reduction or conditions that increase the body’s insulin requirements.

Forxiga may need to be temporarily interrupted before major surgery or during a serious acute illness. The treating healthcare professional should provide instructions on when treatment may be safely restarted.

Dehydration and Low Blood Pressure

Dapagliflozin increases the removal of glucose, sodium and water through the urine. This may cause dehydration, reduced circulating fluid volume or low blood pressure in susceptible patients.

The risk may be higher in older adults, patients taking diuretics, patients with low blood pressure and those experiencing:

• Vomiting or diarrhoea
• Fever or serious illness
• Heavy sweating
• Reduced food or fluid intake
• Strict fluid restriction

Possible symptoms include dizziness, faintness, dry mouth, unusual thirst, weakness, rapid heartbeat or reduced urine output.

Seek medical advice if significant fluid loss or symptoms of dehydration occur. Temporary treatment interruption may be required until the condition has been corrected.

Genital and Urinary Infections

The additional glucose passed through the urine may increase the likelihood of certain genital fungal infections and urinary tract infections.

Possible symptoms of a genital infection include:

• Itching or irritation
• Redness or discomfort
• Unusual genital discharge or odour
• Inflammation around the penis or vaginal area

Possible symptoms of a urinary tract infection include:

• Pain or burning during urination
• Frequent or urgent urination
• Fever or chills
• Back or side pain
• Blood in the urine

Obtain prompt medical advice if these symptoms occur. Severe urinary infection, kidney infection or urosepsis requires urgent assessment.

Fournier’s Gangrene Warning

A rare but serious infection known as necrotising fasciitis of the perineum or Fournier’s gangrene has been reported in patients taking SGLT2 inhibitors.

Seek urgent medical attention for pain, tenderness, redness or swelling around the genitals or the area between the genitals and anus, particularly when accompanied by fever or feeling generally unwell.

This condition requires immediate medical and surgical treatment. Forxiga should be discontinued when Fournier’s gangrene is suspected.

Hypoglycaemia

Forxiga used alone does not usually cause significant hypoglycaemia. However, the risk may increase when dapagliflozin is combined with insulin or a sulfonylurea.

Possible symptoms of low blood glucose include:

• Shaking or sweating
• Hunger
• Rapid heartbeat
• Headache
• Blurred vision
• Anxiety, confusion or mood changes

The doctor may need to review the insulin or sulfonylurea dose. Patients should follow their personalised hypoglycaemia-management plan.

Possible Side Effects

Not everyone experiences side effects. Possible effects associated with dapagliflozin include:

• Genital fungal infection
• Urinary tract infection
• Passing urine more frequently
• Increased urine volume
• Dizziness
• Back pain
• Rash or itching
• Thirst or dry mouth
• Constipation
• Dehydration or low blood pressure
• Temporary changes in kidney-function test results
• Low blood glucose when combined with insulin or a sulfonylurea

Persistent, worsening or troublesome effects should be discussed with a doctor or pharmacist.

Serious Symptoms Requiring Medical Attention

Seek prompt or urgent medical attention if any of the following occurs:

• Symptoms of diabetic ketoacidosis
• Severe dehydration, fainting or very low blood pressure
• Fever with painful urination or back pain
• Severe genital or perineal pain, redness or swelling
• Swelling of the face, lips, tongue or throat
• Difficulty breathing or swallowing
• Very low urine output
• A severe or widespread skin reaction
• Another serious or unexpected reaction

Kidney Function Considerations

Kidney function should be assessed according to the indication and patient’s clinical condition.

In patients with type 2 diabetes, the blood-glucose-lowering effect of dapagliflozin becomes less effective as kidney function declines. The doctor may consider additional glucose-lowering treatment when necessary.

Patients should not independently stop Forxiga solely because they have chronic kidney disease, as dapagliflozin has a separate approved kidney indication. The decision must be based on clinical assessment and the current approved product information.

Medicine Interactions

Tell the doctor and pharmacist about all prescription medicines, non-prescription products, traditional medicines and supplements being used.

Medicines requiring particular consideration include:

• Insulin: combined use may increase the risk of hypoglycaemia.
• Sulfonylureas: medicines such as gliclazide or glimepiride may increase hypoglycaemia risk when combined with Forxiga.
• Diuretics: combined use may increase fluid loss, dehydration and low blood pressure.
• Blood-pressure medicines: additional blood-pressure reduction may occur in susceptible patients.
• Lithium: dapagliflozin may lower blood lithium concentrations, and closer monitoring may be required.
• Other glucose-lowering medicines: the overall diabetes treatment plan may require adjustment.

Do not start, stop or change another medicine without consulting the treating doctor or pharmacist.

Pregnancy and Breastfeeding

Patients who are pregnant, planning a pregnancy or think they may be pregnant should inform their doctor before taking Forxiga.

When pregnancy is detected, dapagliflozin should be discontinued under medical direction. It is not recommended during the second and third trimesters because of potential effects on the developing kidneys.

Forxiga should not be used while breastfeeding because a risk to the nursing infant cannot be excluded.

Use in Children and Adolescents

The approved Malaysian indications referenced on this page relate to adult patients. Forxiga 10mg should not be supplied to a child or adolescent unless specifically prescribed under the current approved Malaysian product information by an appropriate healthcare professional.

Storage Instructions

• Keep the medicine out of the sight and reach of children.
• Keep the tablets in their original blister packaging until required.
• Store according to the conditions printed on the Malaysian carton and package insert.
• Do not use tablets that appear wet, damaged, discoloured or deteriorated.
• Do not use after the expiry date printed on the supplied packaging.
• Product appearance, packaging, batch number and expiry date may vary between supplied batches.

Frequently Asked Questions

What is the active ingredient in Forxiga 10mg?

Each Forxiga 10mg film-coated tablet contains dapagliflozin propanediol equivalent to dapagliflozin 10mg.

What type of medicine is Forxiga?

Forxiga is a sodium-glucose co-transporter 2 inhibitor, commonly abbreviated as an SGLT2 inhibitor.

What is Forxiga 10mg used for?

Forxiga is prescribed for selected adults with type 2 diabetes mellitus, symptomatic chronic heart failure or chronic kidney disease.

Is Forxiga only a diabetes medicine?

No. Although dapagliflozin was initially used for type 2 diabetes, Forxiga also has approved indications for symptomatic chronic heart failure and chronic kidney disease in adults.

Can patients without diabetes use Forxiga?

Forxiga may be prescribed for selected adults with heart failure or chronic kidney disease regardless of whether they have type 2 diabetes. Suitability must be determined by the treating doctor.

How does Forxiga lower blood glucose?

Dapagliflozin blocks SGLT2 proteins in the kidneys, allowing additional glucose to leave the body through the urine.

Is Forxiga a weight-loss tablet?

No. Forxiga is not approved as a general weight-loss medicine. Any weight change during treatment should be discussed with the treating healthcare professional.

Is Forxiga used for type 1 diabetes?

No. Forxiga should not be used to treat type 1 diabetes because of the increased risk of diabetic ketoacidosis.

Can Forxiga treat diabetic ketoacidosis?

No. Forxiga must not be used to treat diabetic ketoacidosis. SGLT2 inhibitors may increase the risk of DKA in certain circumstances.

How often is Forxiga 10mg taken?

The approved reference dosage is generally one 10mg tablet once daily. Patients must follow the dosage shown on their individual prescription and dispensing label.

Can Forxiga be taken with food?

Yes. Forxiga may be taken with or without food and should be swallowed with water.

Why can Forxiga cause genital infections?

Forxiga increases the amount of glucose removed through the urine. Additional glucose around the genital and urinary areas may increase the likelihood of certain fungal or urinary infections.

Can Forxiga cause low blood glucose?

Dapagliflozin used alone has a relatively low risk of hypoglycaemia. The risk may increase when it is combined with insulin or a sulfonylurea.

Why might Forxiga be stopped before surgery?

Major surgery, fasting and serious illness may increase the risk of diabetic ketoacidosis. The treating team may temporarily interrupt Forxiga and monitor ketone levels until the patient is clinically stable.

What is the Malaysian registration number for Forxiga 10mg?

The Malaysian registration number is MAL14015014ARZ.

Who manufactures Forxiga 10mg?

The Malaysian registration record lists AstraZeneca Pharmaceuticals LP, United States, as the manufacturer and AstraZeneca Sdn. Bhd. as the product registration holder.

How many tablets are supplied in one pack?

The P-Hub listing contains 28 tablets, supplied as two blister strips of 14 tablets.

Can pharmacies request Forxiga through P-Hub?

Forxiga 10mg Dapagliflozin Tablets 28s is listed in the P-Hub B2B catalogue for approved pharmacy members. Quotation, ordering eligibility and supply are subject to P-Hub membership requirements, prescription medicine controls and current stock availability.

Prescription Medicine Notice

Forxiga 10mg is a prescription medicine. It should only be supplied, dispensed and used according to applicable Malaysian requirements and the directions of a registered doctor or pharmacist.

The information on this page is provided for pharmacy catalogue and professional product-reference purposes. It does not replace an individual medical assessment, prescription, approved Malaysian package insert or advice from a qualified healthcare professional.

Product appearance, packaging, batch number, availability and expiry date may vary. Verify all information on the physical product packaging and approved insert before dispensing or use.

Product Information Sources

• National Pharmaceutical Regulatory Agency Malaysia – Forxiga Registration Renewal Record
  
• National Pharmaceutical Regulatory Agency Malaysia – Forxiga Chronic Kidney Disease Indication
  
• National Pharmaceutical Regulatory Agency Malaysia – Forxiga Symptomatic Chronic Heart Failure Indication
  
• AstraZeneca – Forxiga 10mg Professional Product Information
  
• National Pharmaceutical Regulatory Agency Malaysia – Dapagliflozin Diabetic Ketoacidosis Safety Communication
  

Product information last reviewed: 11 July 2026.